Psychiatric complications of treatment with corticosteroids: review with case report.
نویسندگان
چکیده
Corticosteroids are widely used in modern medicine but can result in troubling psychiatric side-effects. Physicians and other medical professionals should be aware of the potential for these side-effects, possible means of prevention, and efficacious treatments. Herein, we review adult case report data published during the past quarter-century on adverse corticosteroid-induced psychiatric effects, and present a case of corticosteroid-induced psychotic depression. PubMed and PsychLit databases were searched using the terms 'corticosteroids', 'steroids', and the generic names of corticosteroid medications with terms for psychiatric symptoms or syndromes, including psychosis, mania, hypomania, depression, apathy, anxiety, panic, depersonalization, delirium, confusion, hallucinations, delusions, paranoia, cognitive impairment and dementia. Fifty-five cases and a number of clinical trials investigating the incidence and treatment of these psychiatric symptoms and syndromes were identified. Data on incidence, drug dose, risk factors, course of illness and treatment (when present) were tabulated. We conclude that the cumulative data indicate that psychiatric complications of corticosteroid treatment are not rare and range from clinically significant anxiety and insomnia, to severe mood and psychotic disorders, delirium and dementia. While tapering or discontinuation of the corticosteroid treatment may remedy these adverse side-effects, psychotropic medications are often required because of the medical necessity of the corticosteroid or the severity of the psychiatric symptom. Further studies are needed to better understand the deleterious psychiatric effects associated with corticosteroids.
منابع مشابه
Trichobezoar Causing Gastric Perforation: A Case Report
Trichobezoars are impactions of swallowed hairs in the stomach and occasionally in the intestine. They occur in emotionally disturbed, depressed, or mentally retarded patients who have trichotillomania and trichophagia. Trichobezoars are usually diagnosed on CT scan or upper GI endoscopy. They can give rise to complications like gastroduodenal ulceration, haemorrhage, perforation, peritonitis, ...
متن کاملSclopetaria; Systematic Review and Case Report of the Prognosis and Treatment Mechanism
Purpose: To report a case of traumatic sclopetaria and to present a review on the mechanism of traum, disease prognosis, and treatment methods. Case Report: A 18-year-old male was assaulted with an air gun from a 3-meter distance. The projectile had entered the left orbit without rupturing the globe. He presented to the emergency room with BCVA of hand motion OS and 20/20 OD. He had a left rAPD...
متن کاملPleural Space Complications from Tuberculous Empyema: A Case Report and Short Literature Review
Tuberculous empyema (TE) is an uncommon form of pleural tuberculous (TB). Although the incidence of TE has significantly decreased, it still threatens public health. Patients with TE experience a protracted illness and significant morbidity and mortality risk. Male sex is a significant risk factor for TE. Herein, we report an adult case of TE admitted to a tertiary care hospital of Iran with cl...
متن کاملAcute Suppurative Thyroiditis with Thyroid Abscess (Case Report and Review of the Literature)
Introduction: Thyroid gland is well known to resist infections by rich blood supply and lymphatic drainage, high glandular content of iodine which can be bactericidal and separation of the gland from other structures of neck. Primary thyroid abscess resulting from acute suppurative thyroiditis (AST) is an unusual type of head and neck infection and it is a rare condotion in children so that p...
متن کاملVagus nerve shwannoma presented with long-term cachexia: report of a case and review of literature
Abstract Intraabdominal schwannomas are rare tumors that may arise from viscera or abdominal wall. The rarity accompanied by occurrence in odds places may make their diagnosis difficult and delayed. We present a case of distal paraesophageal schwannoma with long-term cachexia. A34-year-old man presented with long-lasting vomiting, dysphagia, and progressive cachexia for four years. Multip...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Psychiatry and clinical neurosciences
دوره 65 6 شماره
صفحات -
تاریخ انتشار 2011